用于存储的原子开关。

An atomic switch for memory.

作者信息

Sweatt J David

机构信息

Department of Neurobiology and McKnight Brain Institute, University of Alabama-Birmingham, Birmingham, AL 35294, USA.

出版信息

Cell. 2007 Apr 6;129(1):23-4. doi: 10.1016/j.cell.2007.03.021.

DOI:10.1016/j.cell.2007.03.021

PMID:17418779

Abstract

Molecular genetic techniques are beginning to bring about a detailed understanding of the biochemical processes underlying complex cognitive phenomena such as memory, with investigations approaching atomic-level resolution. An excellent example of this is provided in this issue of Cell by Costa-Mattioli et al. (2007), whose results implicate a single protein dephosphorylation event in the control of long-term memory formation in mice.

摘要

分子遗传学技术正开始使人们对诸如记忆等复杂认知现象背后的生化过程有更详细的了解，相关研究正接近原子水平分辨率。本期《细胞》杂志中科斯塔 - 马蒂奥利等人（2007年）的研究就是一个很好的例子，他们的结果表明小鼠长期记忆形成的控制涉及单个蛋白质去磷酸化事件。