Marks John H
Department of Pediatrics and Human Development, Michigan State University College of Human Medicine, East Lansing, Michigan, USA.
Paediatr Respir Rev. 2007 Mar;8(1):17-23. doi: 10.1016/j.prrv.2007.02.003. Epub 2007 Mar 21.
Clearance of infected airway secretions is essential to preserve lung function in patients with cystic fibrosis (CF). Although the value of regular airway clearance treatments has been shown in many studies, adherence to the prescribed treatments is not very good (see Making airway clearance successful, pp. 000-000). In the past the only method available was conventional chest physiotherapy (CCPT; also known as manual percussion and postural drainage). CCPT remains the 'gold standard' of airway clearance methods and may be the best choice for some patients, such as infants and young children. However, the many newer methods of airway clearance available now allow CF patients and their families to choose the techniques and devices that best suits them. Most of the newer airway clearance devices have been studied in comparison to standard chest physiotherapy and most studies show no advantage of one method over another. This review will describe newer airway clearance devices available for CF patients and discuss evidence for the effectiveness of these devices compared to standard chest physiotherapy.
清除受感染的气道分泌物对于囊性纤维化（CF）患者维持肺功能至关重要。尽管许多研究已表明定期进行气道清除治疗的价值，但对规定治疗的依从性并不理想（见《使气道清除成功》，第000 - 000页）。过去，唯一可用的方法是传统胸部物理治疗（CCPT；也称为手法叩击和体位引流）。CCPT仍然是气道清除方法的“金标准”，可能是某些患者（如婴幼儿）的最佳选择。然而，现在有许多更新的气道清除方法，使CF患者及其家人能够选择最适合他们的技术和设备。与标准胸部物理治疗相比，大多数更新的气道清除设备都经过了研究，大多数研究表明一种方法并不比另一种方法更具优势。本综述将描述可供CF患者使用的更新的气道清除设备，并讨论这些设备与标准胸部物理治疗相比有效性的证据。
