Glöckner R, Karge E
Institute of Pharmacology and Toxicology, Friedrich Schiller University Jena, Germany.
J Exp Anim Sci. 1991;34(3):93-8.
Young (70-120 d) and old (11-13 month) Uje:WIST rats were exposed to the strong stressor "chronic restraint" before and/or during gestation. Most adverse effects on pregnancy outcome were induced in young dams stressed before and during gestation (prolonged duration of pregnancy, lower body mass of the newborn pups). In old dams chronic restraint did not further deteriorate the age-dependent poor reproductive performance, but even rejuvenated it, if stress exposure was limited to the premating period.
年轻（70 - 120日龄）和年老（11 - 13月龄）的Uje:WIST大鼠在妊娠前和/或妊娠期间受到强烈应激源“慢性束缚”。对妊娠结局的大多数不利影响是在妊娠前和妊娠期间受到应激的年轻母鼠中诱发的（妊娠期延长，新生幼崽体重较低）。在老年母鼠中，慢性束缚并没有进一步恶化与年龄相关的不良生殖性能，但如果应激暴露仅限于交配前期，甚至会使其恢复活力。
