Sorel J E, Heiss G, Tyroler H A, Davis W B, Wing S B, Ragland D R
Department of Epidemiology, School of Public Health, University of California, Berkeley 94720.
Epidemiology. 1991 Sep;2(5):348-52. doi: 10.1097/00001648-199109000-00006.
Separate studies using data from the second National Health and Nutrition Examination Survey, 1976-1980 (NHANES II) have shown that blacks in the United States have higher blood lead levels than whites and that blood lead is positively related to blood pressure. Based on these reports, we examined data from NHANES II to determine the extent to which race differences in blood pressure were explained by elevated blood lead levels in blacks. Regression analyses, with race as an indicator variable, were used to estimate the contribution of blood lead to black-white differences in blood pressure. The overall effect of blood lead on race differences in blood pressure was small, reflecting, in part, the magnitude of race differences in blood lead and in the association of blood lead and blood pressure. Nevertheless, a pronounced and consistent effect of lead on race differences in blood pressure was found among the poor, particularly women.
利用1976 - 1980年第二次全国健康与营养检查调查（NHANES II）的数据进行的单独研究表明，美国黑人的血铅水平高于白人，且血铅与血压呈正相关。基于这些报告，我们检查了NHANES II的数据，以确定黑人血铅水平升高在多大程度上解释了血压的种族差异。以种族作为指示变量进行回归分析，以估计血铅对黑人和白人血压差异的影响。血铅对血压种族差异的总体影响较小，部分反映了血铅的种族差异程度以及血铅与血压之间的关联程度。然而，在贫困人口中，尤其是女性中，发现铅对血压种族差异有显著且一致的影响。
