Ottobrelli A, Lagget M, Arrigoni A, Gindro T, Bosio C, Balbo G, Rizzetto M
Divisione di Gastroenterologia, Ospedale S. Giovanni Battista, Molinette - Torino.
Minerva Gastroenterol Dietol. 1991 Apr-Jun;37(2):131-4.
We report the case of a patient with recurrent subocclusive episodes and diarrhea (no malabsorption) associated with ascites, in the absence or liver, kidney or heart disease. The demonstration of hypereosinophilia in the peripheral blood and in the ascites fluid and the failure to identify parasitic or haematological disorders have led to a through examination of the stomach (Endoscopy, Echoendoscopy), small bowel (X-rays and Computerized Axial Tomography) and colon (colonoscopy) in a search for parietal lesions. The absence of segmental lesions and the observation of CAT images of diffuse, regular thickening of the ileum and of the mesentery, coupled with the monotonous clinical history spanning over three decades, have led to a diagnosis of eosinophilic gastroenteritis with involvement of the serosal layer. Serosal involvement is rare in eosinophilic disease of the gut; in analogy with other cases reported in the literature, steroids have improved clinical symptoms and normalized the hematological picture.
我们报告了一例患者,其反复出现亚闭塞性发作并伴有腹泻(无吸收不良),同时伴有腹水,且无肝脏、肾脏或心脏疾病。外周血和腹水中嗜酸性粒细胞增多,且未发现寄生虫或血液系统疾病,因此对胃(内镜检查、超声内镜检查)、小肠(X线和计算机断层扫描)和结肠(结肠镜检查)进行了全面检查,以寻找壁层病变。未发现节段性病变,计算机断层扫描图像显示回肠和肠系膜弥漫性、规则性增厚,再加上长达三十年的单调临床病史,最终诊断为累及浆膜层的嗜酸性胃肠炎。浆膜受累在肠道嗜酸性疾病中较为罕见;与文献中报道的其他病例类似,使用类固醇药物后临床症状有所改善,血液学指标也恢复正常。