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人乳中的蛋白质。

Proteins in human milk.

作者信息

López Alvarez María José

出版信息

Breastfeed Rev. 2007 Mar;15(1):5-16.

Abstract

The human baby is born extremely immature, with its major organs and immune system not fully developed. for its survival, the infant depends on an extraordinarily well-adapted evolutionary strategy shared by all mammals: breastfeeding. But what does milk contain that makes it so essential for the newborn and how does it provide immunity, nutrition, and a source for optimal growth? Human milk is a very complex living fluid which comprises proteins, carbohydrates, lipids, cells and other biologically important components. These milk components interact synergistically with each other and their environment (the infant's gut) at a biomolecular level with the final result being that breastmilk feeds and protects the newborn. This article summarises the key characteristics of breastmilk proteins and describes their functions as critical molecules conferring human milk with its diverse bioactive properties. Also presented are some of the factors which hav an influence on the quantity and quality of breastmilk proteins.

摘要

人类婴儿出生时极其不成熟,其主要器官和免疫系统尚未完全发育。为了生存,婴儿依赖于所有哺乳动物都具备的一种高度适应的进化策略:母乳喂养。但是,母乳中究竟含有什么成分使其对新生儿如此至关重要,它又是如何提供免疫力、营养以及实现最佳生长的来源呢?母乳是一种非常复杂的生物流体,包含蛋白质、碳水化合物、脂质、细胞和其他具有重要生物学意义的成分。这些母乳成分在生物分子水平上相互协同作用,并与它们所处的环境(婴儿的肠道)相互作用,最终结果是母乳为新生儿提供营养并保护他们。本文总结了母乳蛋白质的关键特性,并描述了它们作为赋予母乳多种生物活性特性的关键分子的功能。还介绍了一些影响母乳蛋白质数量和质量的因素。

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