Daoud Wafa, Zeglaoui Faten, Kastalli Sarra, Elfekih Nadia, Fazaa Bécima, Loueslati Mohamed, Belkahia Chalbi, Kamoun Mohamed R
Service de Dermatologie, Hôpital Charles Nicolle, Tunis, Tunisie.
Tunis Med. 2007 Jan;85(1):39-41.
To discuss, through a retrospective study, the epidemiological and clinical aspects and the causative agents of fixed drug eruption.
Thirteen cases were collected retrospectively during 11 years. There were 10 females and 3 males with a mean age of 44 years.
The lesions correspond to erythematous plaques which fade to leave slate-brawn macules in all cases. The most frequent localizations were limbs (12 cases), trunk (6 cases), face (3 cases) ans external genitals (3 cases). Sulfonamides were the most frequent responsible drugs in our series (7 cases).
Fixed drug eruption is characterized by one or more erythematous plaques which recur in the same places after challenge. Sulfonamides are actually the most frequent causative drugs in the different series.
