Bi Yun-Mei, Bi Xu-Bin, Fang A, Zhao Qian-Rong
Department of Chemistry, Yunnan Normal University, Kunming 650092, China.
Arch Pharm Res. 2007 Mar;30(3):267-9. doi: 10.1007/BF02977604.
A new pyrone derivative, 7, 9-dihydroxy-10-methyl-2H, 4aH, 6H, 10bH-pyrano[5,6-c][2]ben-zopyran-2,6-dione (1), was isolated from a culture broth of a strain of the fungus Cephalosporium sp. AL031, together with three known compounds, 3-acetyl-7-hydroxy-5-methoxyl-3H-isobenzofuran-1-one (2), vermopyrone (3), and 5-methylmellein (4). Their structures were elucidated by spectroscopic analysis including MS and 2D-NMR. Compounds 2, 3, and 4 are reported for the first time from fermentation broth of this fungus through the present study.
从真菌头孢霉属菌株AL031的培养液中分离出一种新的吡喃酮衍生物，7,9-二羟基-10-甲基-2H,4aH,6H,10bH-吡喃并[5,6-c][2]苯并吡喃-2,6-二酮（1），以及三种已知化合物，3-乙酰基-7-羟基-5-甲氧基-3H-异苯并呋喃-1-酮（2）、蛭菌素（3）和5-甲基麦角硫因（4）。通过包括质谱和二维核磁共振在内的光谱分析确定了它们的结构。通过本研究首次报道了化合物2、3和4存在于该真菌的发酵液中。
