一种源自内生真菌盘菌青霉PSU-A71的新型吡喃酮衍生物。

A new pyrone derivative from the endophytic fungus Penicillium paxilli PSU-A71.

作者信息

Rukachaisirikul Vatcharin, Kaeobamrung Juthanat, Panwiriyarat Wannarat, Saitai Pimchanok, Sukpondma Yaowapa, Phongpaichit Souwalak, Sakayaroj Jariya

机构信息

Department of Chemistry, Faculty of Science, Prince of Songkla University, Songkla, Thailand.

出版信息

Chem Pharm Bull (Tokyo). 2007 Sep;55(9):1383-4. doi: 10.1248/cpb.55.1383.

DOI:10.1248/cpb.55.1383

PMID:17827767

Abstract

One new pyrone derivative, named penicillone (1), together with paxilline, pyrenocines A (2) and B (3) were isolated from the endophytic fungus Penicillium paxilli PSU-A71. The structures were elucidated by spectroscopic methods. Pyrenocine B (3) mildly inhibited the growth of Microsporum gypseum SH-MU-4 with a MIC value of 32 microg/ml.

摘要

从内生真菌青霉PSU - A71中分离出一种新的吡喃酮衍生物，命名为青霉酮（1），以及帕西丁、黄绿青霉素A（2）和B（3）。通过光谱方法阐明了其结构。黄绿青霉素B（3）对石膏样小孢子菌SH - MU - 4的生长有轻度抑制作用，MIC值为32微克/毫升。