Trisuwan Kongkiat, Rukachaisirikul Vatcharin, Sukpondma Yaowapa, Preedanon Sita, Phongpaichit Souwalak, Rungjindamai Nattawut, Sakayaroj Jariya
Department of Chemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla, 90112, Thailand.
J Nat Prod. 2008 Aug;71(8):1323-6. doi: 10.1021/np8002595. Epub 2008 Jul 23.
Nigrospoxydons A-C (1- 3) and nigrosporapyrone (4), four new metabolites, were isolated from the marine-derived fungus Nigrospora sp. PSU-F5 together with nine known compounds. Their structures were elucidated by spectroscopic methods, mainly 1D and 2D NMR spectroscopic techniques. The antibacterial activity against the standard Staphylococcus aureus ATCC 25923 and methicillin-resistant S. aureus was evaluated.
从海洋来源的真菌黑孢霉PSU-F5中分离出四种新的代谢产物——黑孢霉毒素A-C（1-3）和黑孢霉吡喃酮（4），以及九种已知化合物。通过光谱方法，主要是一维和二维核磁共振光谱技术对它们的结构进行了阐明。评估了它们对标准金黄色葡萄球菌ATCC 25923和耐甲氧西林金黄色葡萄球菌的抗菌活性。
