Banaag April R, Tius Marcus A
Department of Chemistry, University of Hawaii, 2545 The Mall, Honolulu, Hawaii 96822, USA.
J Am Chem Soc. 2007 May 2;129(17):5328-9. doi: 10.1021/ja069342g. Epub 2007 Apr 11.
A 1,3- or a 1,4- axial -butyldimethylsilyloxy substituent on the pyranose derived chiral auxiliary for the allene ether Nazarov cyclization leads to products in high optical purity. α-Pyranose and β-pyranose derived auxiliaries lead to enantiomeric products.
用于丙二烯醚纳扎罗夫环化反应的吡喃糖衍生手性助剂上的1,3-或1,4-轴向-丁基二甲基甲硅烷氧基取代基可生成高光学纯度的产物。α-吡喃糖和β-吡喃糖衍生的助剂可生成对映体产物。