创伤后应激障碍的功能性神经影像学研究
Functional neuroimaging in post-traumatic stress disorder.
作者信息
Bremner J Douglas
机构信息
Emory University, Atlanta, GA 30306, USA.
出版信息
Expert Rev Neurother. 2007 Apr;7(4):393-405. doi: 10.1586/14737175.7.4.393.
Abstract
Traumatic stress has a broad range of effects on brain function. Brain areas implicated in the stress response include the amygdala, hippocampus, and prefrontal cortex. Brain studies in patients with post-traumatic stress disorder replicated findings in animal studies by finding alterations in these brain areas. Brain areas implicated in post-traumatic stress disorder play an important role in the stress response as well as memory, highlighting the important interplay between memory and the traumatic stress response. Future studies are required to assess the relationship between recovery from traumatic stress and changes in brain function.
摘要
创伤应激对脑功能有广泛影响。与应激反应相关的脑区包括杏仁核、海马体和前额叶皮质。创伤后应激障碍患者的脑部研究通过发现这些脑区的改变，重现了动物研究中的结果。与创伤后应激障碍相关的脑区在应激反应以及记忆方面都发挥着重要作用，凸显了记忆与创伤应激反应之间的重要相互作用。未来需要开展研究来评估创伤应激恢复与脑功能变化之间的关系。
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