Du Plessis C J, Keller N, Millward I R
Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort 0110, South Africa.
J Small Anim Pract. 2007 May;48(5):275-8. doi: 10.1111/j.1748-5827.2006.00262.x. Epub 2007 Apr 8.
Spirocerca lupi is a nematode mainly affecting dogs but has been found in other animals, particularly carnivores. Anatomical areas of typical and aberrant migration vary. This report describes four cases of Spirocerca lupi causing neurological symptoms, similar to thoracolumbar disc syndrome, as a result of aberrant migration of the nematode into the spinal canal. In two of the cases, the nematode could be demonstrated intraoperatively. The third was discovered on post-mortem examination, while the fourth case displayed compelling evidence of Spirocerca lupi involvement. Surgical removal of the Spirocerca lupi nematode would be the treatment of choice in cases of spinal migration, with therapeutic and preventive treatment with doramectin instituted to treat remote sites and prevent re-infection. In areas endemic for spirocercosis, Spirocerca lupi should be considered as an important differential diagnosis in cases that are presented with clinical signs suggestive of a spinal cord lesion.
狼旋尾线虫是一种主要感染犬类的线虫,但在其他动物尤其是食肉动物中也有发现。典型和异常移行的解剖部位各不相同。本报告描述了4例由于狼旋尾线虫异常移行至椎管而导致神经症状(类似于胸腰椎间盘综合征)的病例。其中2例在手术中发现了线虫。第3例是在尸检时发现的,而第4例有确凿证据表明有狼旋尾线虫感染。对于脊髓移行的病例,手术切除狼旋尾线虫是首选治疗方法,同时使用多拉菌素进行治疗和预防性治疗,以治疗远处部位并防止再次感染。在旋尾线虫病流行地区,对于出现提示脊髓病变临床症状的病例,应将狼旋尾线虫视为重要的鉴别诊断对象。