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病例报告:一只患有广州管圆线虫病的犬出现颅内和脊髓蛛网膜下腔出血。

Case report: Intracranial and spinal subarachnoid hemorrhage in a dog with Angiostrongylosis.

作者信息

Santifort Koen M, den Toom Marjolein, Garosi Laurent, Carrera Ines

机构信息

IVC Evidensia Small Animal Referral Hospital Arnhem, Neurology, Arnhem, Netherlands.

IVC Evidensia Small Animal Referral Hospital Hart van Brabant, Neurology, Waalwijk, Netherlands.

出版信息

Front Vet Sci. 2023 May 24;10:1190792. doi: 10.3389/fvets.2023.1190792. eCollection 2023.

Abstract

A 1-year-old male intact Staffordshire terrier, born and raised in the Netherlands, was presented with a 3-week history of progressive lethargy and spinal, predominantly cervical, hyperesthesia. Other than hyperthermia and cervical hyperesthesia, general and neurological examination did not reveal any abnormalities. Comprehensive hematological and biochemical tests were considered normal. Magnetic resonance imaging of the craniocervical region revealed heterogeneity of the subarachnoid space, characterized by pre-contrast T1W hyperintensity, corresponding to a T2* signal void. Extending from the caudal cranial fossa to the level of the third thoracic vertebra, there were uneven patchy extra-parenchymal lesions that caused mild spinal cord compression, most marked at the level of C2. At this level, the spinal cord showed an ill-defined hyperintense T2W intramedullary lesion. Mild intracranial and spinal meningeal contrast enhancement was evident on post-contrast T1W images. Subarachnoid hemorrhage was suspected, and further diagnostic tests including Baermann coprology resulted in a diagnosis of hemorrhagic diathesis caused by an infection. The dog rapidly responded to treatment with corticosteroids, analgesic medication, and antiparasitic treatment. Follow-up over 6 months yielded complete clinical remission and repeatedly negative Baermann tests. This case report details clinical and magnetic resonance imaging findings in a dog with subarachnoid hemorrhage associated with an infection.

摘要

一只1岁的未绝育斯塔福郡斗牛梗,在荷兰出生并长大,出现了3周的进行性嗜睡和脊柱(主要是颈部)感觉过敏病史。除了体温过高和颈部感觉过敏外,全身和神经系统检查未发现任何异常。综合血液学和生化检查被认为正常。颅颈区域的磁共振成像显示蛛网膜下腔不均匀,表现为对比前T1加权像高信号,对应T2*信号缺失。从颅后窝尾部延伸至第三胸椎水平,有不均匀的斑片状脑实质外病变,导致轻度脊髓受压,在C2水平最为明显。在这个水平,脊髓显示出边界不清的T2加权像髓内高信号病变。对比后T1加权像上可见轻度颅内和脊髓脑膜强化。怀疑有蛛网膜下腔出血,进一步的诊断测试包括贝尔曼粪便检查,结果诊断为由感染引起的出血素质。这只狗对皮质类固醇、止痛药物和抗寄生虫治疗反应迅速。6个月的随访显示临床完全缓解,贝尔曼测试反复阴性。本病例报告详细描述了一只患有与感染相关的蛛网膜下腔出血的狗的临床和磁共振成像表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df33/10244777/beec9001303a/fvets-10-1190792-g001.jpg

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