Activated innate immune system in irritable bowel syndrome?
作者信息
Langhorst J, Wieder A, Michalsen A, Musial F, Dobos G J, Rueffer A
出版信息
Gut. 2007 Sep;56(9):1325-6. doi: 10.1136/gut.2007.125005. Epub 2007 Apr 11.
Abstract
摘要
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NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2.NOD2/CARD15介导抗菌肽人β-防御素-2的诱导。
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NF-kappaB- and AP-1-mediated induction of human beta defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917: a novel effect of a probiotic bacterium.大肠杆菌Nissle 1917通过NF-κB和AP-1介导诱导肠上皮细胞中人β-防御素-2：一种益生菌的新作用
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Inducible and constitutive beta-defensins are differentially expressed in Crohn's disease and ulcerative colitis.诱导型和组成型β-防御素在克罗恩病和溃疡性结肠炎中表达不同。
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5
Human beta-defensin 2 but not beta-defensin 1 is expressed preferentially in colonic mucosa of inflammatory bowel disease.人β-防御素2而非β-防御素1在炎症性肠病的结肠黏膜中优先表达。
Eur J Gastroenterol Hepatol. 2002 Jul;14(7):745-52. doi: 10.1097/00042737-200207000-00006.
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Increased mast cells in the irritable bowel syndrome.肠易激综合征中肥大细胞增多。
Neurogastroenterol Motil. 2000 Oct;12(5):449-57. doi: 10.1046/j.1365-2982.2000.00221.x.
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A peptide antibiotic from human skin.一种来自人类皮肤的肽抗生素。
Nature. 1997 Jun 26;387(6636):861. doi: 10.1038/43088.
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Symptoms of irritable bowel syndrome in ulcerative colitis in remission.溃疡性结肠炎缓解期的肠易激综合征症状。
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Studies on the mechanism of bowel disturbance in ulcerative colitis.溃疡性结肠炎肠道紊乱机制的研究。
Gastroenterology. 1987 Nov;93(5):934-40. doi: 10.1016/0016-5085(87)90554-3.
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