[绍兴市无偿献血人群戊型肝炎病毒感染情况]
[Hepatitis E virus infection in population of non-remunerate blood donors in Shaoxing].
作者信息
Sang Lie-yong, Zhuang Pei-fen, Fu Li-qiang, Liu Yi, Ge Sheng-xiang, Zhang Jun
机构信息
Shaoxing Blood Center, Shaoxing 312041, China.
出版信息
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2007 Mar;21(1):29-31.
OBJECTIVE
To investigate the incidence of HEV infection in population of non-remunerate blood donors in Shaoxing.
METHODS
Blood specimens from 3701 non-remunerate blood donors were collected, ELISA were used to study anti-HEV IgG and IgM antibodies, RT-PCR were further used to study HEV RNA in samples from donors whose anti-HEV IgM was positive.
RESULTS
Anti-HEV IgG positive rate was 29.19% (1107/3701), anti-HEV IgM positive rate was 1.35% (50/3701) among non-remunerate blood donors in Shaoxin. Six cases were positive for HEV RNA. The positive rate was 0.16% (6/3701), and all the 6 cases belonged to HEV genotype 1. Different seasons showed no interference on the positive rate of IgG and IgM.
CONCLUSION
The detecting and studying of HEV infection among donors was important to ensure the safety of blood products and blood transfusion.
目的
调查绍兴市无偿献血人群中戊型肝炎病毒（HEV）感染情况。
方法
采集3701名无偿献血者的血液标本，采用酶联免疫吸附测定（ELISA）检测抗HEV IgG和IgM抗体，对其中抗HEV IgM阳性者的标本进一步采用逆转录聚合酶链反应（RT-PCR）检测HEV RNA。
结果
绍兴市无偿献血人群中抗HEV IgG阳性率为29.19%（1107/3701），抗HEV IgM阳性率为1.35%（50/3701）。6例HEV RNA阳性，阳性率为0.16%（6/3701），且6例均为HEV 1型。不同季节对IgG和IgM阳性率无影响。
结论
检测和研究献血者中的HEV感染情况对于确保血液制品及输血安全具有重要意义。
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