Hale Earlie McClain, Smith Eva, St James James, Wojner-Alexandrov Anne W
Clarion Health Partners, Methodist Hosital, Indianapolis, Indiana, USA.
Geriatr Nurs. 2007 Mar-Apr;28(2):104-11. doi: 10.1016/j.gerinurse.2006.10.002.
We sought to determine the effect of a natural laxative mixture compared with daily prescribed laxatives on bowel movement frequency in elderly long-term care residents. Secondary endpoints included ease of administration and costs of the natural laxative. A randomized controlled trial comparing the effect of the Beverley-Travis natural laxative mixture to prescribed laxatives was conducted over an 8-week period. Subjects were randomized to treatment and control groups; control subjects continued on regularly prescribed laxatives, and treatment group subjects discontinued prescribed laxatives and received 2 tablespoons of the natural laxative mixture twice a day for the remaining 4-week period. Bowel movement frequency and consistency were collected, and ease of natural laxative administration as well as costs associated with use of the natural or prescribed laxatives were calculated. The study included 45 residents, with 34 completing the 8-week study period (16 treatment group subjects and 18 control subjects). Treatment group subjects had a significant increase in average number of bowel movements from 15.5 to 22.2 (P = .007) following initiation of the natural laxative, and no difference in bowel movement frequency was observed among control subjects (P = NS). The natural laxative mixture was rated as "easy" or "very easy" to administer by 90%-92% of nurses, and cost savings of $103.04 was estimated. The Beverley-Travis natural laxative mixture, given at a dosage of 2 tablespoons twice daily, is easy to use, cost-effective, and more effective than daily prescribed laxatives at producing normal bowel movements.
我们试图确定一种天然泻药混合物与每日规定使用的泻药相比，对老年长期护理居民排便频率的影响。次要终点包括天然泻药的给药便利性和成本。一项比较贝弗利 - 特拉维斯天然泻药混合物与规定泻药效果的随机对照试验在8周内进行。受试者被随机分为治疗组和对照组；对照组受试者继续按常规服用规定的泻药，治疗组受试者停用规定的泻药，并在剩余的4周内每天服用2汤匙天然泻药混合物两次。收集排便频率和粪便稠度数据，并计算天然泻药的给药便利性以及使用天然或规定泻药的相关成本。该研究纳入了45名居民，其中34名完成了为期8周的研究期（16名治疗组受试者和18名对照组受试者）。开始使用天然泻药后，治疗组受试者的平均排便次数从15.5次显著增加至22.2次（P = .007），而对照组受试者的排便频率未观察到差异（P = 无显著性差异）。90% - 92%的护士将天然泻药混合物的给药评定为“容易”或“非常容易”，估计节省成本103.04美元。每天服用2汤匙的贝弗利 - 特拉维斯天然泻药混合物易于使用、具有成本效益，并且在促进正常排便方面比每日规定使用的泻药更有效。
