Murphy Feilim, Paran Thambipillai Sri, Puri Prem
Children's Research Centre, Our Lady's Hospital for Sick Children, Crumlin, Dublin 4, Ireland.
Pediatr Surg Int. 2007 Jul;23(7):625-32. doi: 10.1007/s00383-007-1900-3. Epub 2007 Mar 13.
We critically analysed the factors known to influence the fertility potential after orchidopexy in children. A comprehensive literature review of all publications in the English language listed in Medline using the words cryptorchidism, undescended testis, orchidopexy, fertility, semen analysis and surgery from 1970 to 2005. In unilateral ectopic, canalicular and emergent testes, as long as the surgery is carried out in early childhood, fertility outcome is good (>90%). The majority of the bilateral abdominal testes are infertile. While unilateral abdominal testes and unilateral absent or vanishing testes have favourable fertility potential, quantification has proven difficult. Despite multiple studies, fertility in crypt orchid tests is still an uncertain issue. Hormonal treatment in conjunction with early surgical correction has not been fully explored. We recommend orchidopexy soon after 6-7 months of age, corrected for term, to maximise the future fertility potential.
我们严格分析了已知影响儿童睾丸固定术后生育潜能的因素。使用“隐睾症”“睾丸未降”“睾丸固定术”“生育力”“精液分析”和“手术”等关键词,对1970年至2005年Medline中列出的所有英文出版物进行了全面的文献综述。对于单侧异位、腹股沟管型和阴囊高位隐睾,只要在儿童早期进行手术,生育结局良好(>90%)。大多数双侧腹腔内隐睾不育。虽然单侧腹腔内隐睾和单侧睾丸缺如或萎缩有较好的生育潜能,但难以进行量化评估。尽管有多项研究,但隐睾症患者的生育力仍是一个不确定的问题。激素治疗联合早期手术矫正尚未得到充分研究。我们建议在足月后6 - 7个月龄后尽快进行睾丸固定术,以最大化未来的生育潜能。