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隐睾症患者的生育能力。

Fertility in undescended testes.

作者信息

Retief P J

出版信息

S Afr Med J. 1977 Oct 1;52(15):610-3.

PMID:21462
Abstract

Since 1956 many children with undescended testes have been treated at the Red Cross War Memorial Children's Hospital in Cape Town, and in this article the conesequent degree of fertility achieved by orchidopexy, the method of treatment, is appraised. In 567 children the condition was unilateral, and in 202 it was bilateral. Assessment of potential fertility in 76 unilateral and in 29 bilateral cases was mainly by semen analysis; the average age of the youths at the time of the examination was 19 years, and parenthood was therefore regarded as an unsuitable criterion for assessment. Four hundred and ninety-two youths had their condition reviewed, and the condition of 587 testes was assessed. The anatomical state of the testes was ascertained to help in the assessment, but also, and of greater importance, to obtain evidence of the usefulness of orchidopexy for cosmetic or psychological benefit. Biopsy of the affected testes, carried out in some, proved to be nor more informative than the anatomical appraisal, with regard to spermatogenesis. Two useful facts emerged from the study. About 10% of bilateral undescended testes are capable of normal spermatogenesis after orchidopexy, and 65% are sterile, while the fertility of persons with unilateral undescended testis is impaired, 28% having little hope of paternity, and 4% no hope at all.

摘要

自1956年以来,许多患有隐睾症的儿童在开普敦的红十字战争纪念儿童医院接受了治疗。在本文中,对睾丸固定术(治疗方法)所带来的生育能力恢复程度进行了评估。567名儿童为单侧隐睾,202名儿童为双侧隐睾。对76例单侧和29例双侧病例的潜在生育能力评估主要通过精液分析进行;接受检查的青年的平均年龄为19岁,因此将为人父母作为评估标准并不合适。492名青年的病情得到复查,587个睾丸的状况得到评估。确定睾丸的解剖状态有助于评估,而且更重要的是,可获取睾丸固定术在美容或心理方面益处的有用证据。对部分受影响的睾丸进行活检,结果证明,就精子发生而言,活检并不比解剖评估提供更多信息。该研究得出了两个有用的结论。约10%的双侧隐睾症患者在接受睾丸固定术后能够正常产生精子,65%的患者不育,而单侧隐睾症患者的生育能力受损,28%的患者几乎没有生育希望,4%的患者完全没有生育希望。

相似文献

1
Fertility in undescended testes.隐睾症患者的生育能力。
S Afr Med J. 1977 Oct 1;52(15):610-3.
2
Orchidopexy in cryptorchidism assessed by clinical, histologic and sperm examinations.通过临床、组织学和精子检查评估隐睾症中的睾丸固定术。
Surg Gynecol Obstet. 1979 Jun;148(6):855-9.
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Fertility index analysis in cryptorchidism.隐睾症的生育指数分析
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Semen analysis of patients who had orchidopexy at or after seven years of age.对7岁及7岁以后接受睾丸固定术的患者进行精液分析。
Lancet. 1988 Nov 5;2(8619):1051-2. doi: 10.1016/s0140-6736(88)90067-0.
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Abnormal germ cell development in cryptorchidism.隐睾症中生殖细胞发育异常。
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引用本文的文献

1
Fertility and unilateral undescended testis in the rat model.大鼠模型中的生育能力与单侧隐睾
Pediatr Surg Int. 1996 Apr;11(4):266-8. doi: 10.1007/BF00178434. Epub 2013 Sep 21.
2
The controversy regarding the need for hormonal treatment in boys with unilateral cryptorchidism goes on: a review of the literature.关于单侧隐睾症男孩是否需要激素治疗的争议仍在继续:文献综述。
Eur J Pediatr. 2013 Jan;172(1):5-8. doi: 10.1007/s00431-012-1711-y. Epub 2012 Mar 7.
3
Endocrinological parameters in experimental unilateral undescended testis.
实验性单侧隐睾的内分泌学参数
Indian J Pediatr. 1999 Mar-Apr;66(2):193-6. doi: 10.1007/BF02761205.