一名甲状腺功能减退孕妇发生自发性卵巢过度刺激。

Spontaneous ovarian hyperstimulation in a pregnant woman with hypothyroidism.

作者信息

Borna Sedigheh, Nasery Azita

机构信息

Department of Perinatology, Vali-asr Hospital, Tehran University of Medical Sciences, Tehran, Iran.

出版信息

Fertil Steril. 2007 Sep;88(3):705.e1-3. doi: 10.1016/j.fertnstert.2006.12.003. Epub 2007 Apr 11.

DOI:10.1016/j.fertnstert.2006.12.003

PMID:17433320

Abstract

OBJECTIVE

This report describes an unusual case in which a naturally conceived pregnancy is associated with spontaneous ovarian hyperstimulation and hypothyroidism.

DESIGN

Case report.

SETTING

University medical center.

PATIENT(S): A 30-year-old pregnant woman with abdominal pain and distension caused by ovarian hyperstimulation.

INTERVENTION(S): Medical management and laparotomy.

MAIN OUTCOME MEASURE(S): Incomplete regression after 3 months.

RESULT(S): Thyroid-stimulating hormone level was elevated. Hormonal studies confirmed hypothyroidism with spontaneous ovarian hyperstimulation. She was given levothyroxine 200 mug/d. Results of the hormonal tests for thyroid function were normal 3 months after treatment, but in this case the ovarian cysts did not regress completely until delivery. Laparotomy and cesarean section were done for both diagnosis and treatment. Ten weeks after delivery ovarian cysts regressed completely.

CONCLUSION(S): Thyroid hormone replacement seems to be the best therapeutic approach in some patients, but, in some, complete resolution of the ovarian cysts does not occur after 3 months.

摘要