Loukas Marios, Clarke Pamela, Tubbs R Shane, Kapos Theodoros, Trotz Margit
Department of Anatomical Sciences, St. George's University, School of Medicine, True Blue Campus, West Indies, Grenada.
Int J Cardiol. 2008 Jan 11;123(2):75-8. doi: 10.1016/j.ijcard.2006.12.070. Epub 2007 Apr 12.
Few families in medicine can claim that more than one of their members contributed significantly to modern-day clinical and research practices. The Swiss family of His can assert that two of their number, Wilhelm His Sr. (1831-1904) and Wilhelm His Jr. (1863-1934) made advancements in medicine that still have an impact on many areas of research and clinical practice today. In 1865, His focused on embryology research and he introduced the term "endothelium" from his observations in embryology. His invented the microtome in 1866, and named the axonal appendages as dendrites. On the other hand His Jr., in 1893, published a 35-page article that described the activity of the embryonic heart and how this understanding is important in comprehending actions in the adult heart. This article contains the description of his best-known discovery, the now eponymous Bundle of His. Modern researchers and clinicians should consider the importance of the work of both Wilhelm His Sr. and Wilhelm His Jr. Advancements in embryological, histological and cardiovascular electrophysiology research can all trace some input back to this father and son.
在医学领域，很少有家族能宣称其家族中有不止一位成员对现代临床和研究实践做出了重大贡献。希斯家族（His family）却可以宣称，他们家族中的两位成员，老威廉·希斯（Wilhelm His Sr., 1831 - 1904）和小威廉·希斯（Wilhelm His Jr., 1863 - 1934）在医学上取得的进展至今仍对许多研究领域和临床实践产生着影响。1865年，希斯专注于胚胎学研究，并根据他在胚胎学中的观察引入了“内皮”一词。1866年，他发明了切片机，并将轴突附属物命名为树突。另一方面，小威廉·希斯在1893年发表了一篇35页的文章，描述了胚胎心脏的活动以及这种理解对理解成体心脏活动的重要性。这篇文章包含了他最著名的发现的描述，即现在以他的名字命名的希氏束。现代研究人员和临床医生应该认识到老威廉·希斯和小威廉·希斯工作的重要性。胚胎学、组织学和心血管电生理学研究的进展都可以追溯到这对父子的一些贡献。
