Samejima Kazuyuki, Doya Kenji
Tamagawa University Brain Science Institute, 6-1-1 Tamagawa-gakuen, Machida, Tokyo, Japan 195-8610.
Ann N Y Acad Sci. 2007 May;1104:213-28. doi: 10.1196/annals.1390.024. Epub 2007 Apr 13.
Reward-related neural activities have been found in a variety of cortical and subcortical areas by neurophysiological and neuroimaging experiments. Here we present a unified view on how three subloops of the corticobasal ganglia network are involved in reward prediction and action selection using different types of information. The motor/premotor-posterior striatum loop is specialized for action-based value representation and movement selection. The orbitofrontal-ventral striatum loop is specialized for object-based value representation and target selection. The lateral prefrontal-anterior striatum loop is specialized for context-based value representation and context estimation. Furthermore, the medial prefrontal cortex (MPFC) coordinates these multiple value representations and actions at different levels of hierarchy by monitoring the error in predictions.
通过神经生理学和神经影像学实验，在各种皮质和皮质下区域发现了与奖励相关的神经活动。在此，我们提出一个统一的观点，即皮质基底神经节网络的三个子环路如何利用不同类型的信息参与奖励预测和动作选择。运动/运动前区-后纹状体环路专门用于基于动作的值表示和运动选择。眶额-腹侧纹状体环路专门用于基于对象的值表示和目标选择。外侧前额叶-前纹状体环路专门用于基于情境的值表示和情境估计。此外，内侧前额叶皮质（MPFC）通过监测预测误差，在不同层次水平上协调这些多种值表示和动作。
