Gandara Beatrice K, Leresche Linda, Mancl Lloyd
Department of Oral Medicine, Box 356370, School of Dentistry, University of Washington, Seattle, Washington 98195, USA.
Ann N Y Acad Sci. 2007 Mar;1098:446-50. doi: 10.1196/annals.1384.022.
The aim of this study was to characterize the normality of menstrual cycles on the basis of progesterone and estradiol levels in self-collected saliva samples. Twenty-two women, ages 19-40 years, self-collected whole unstimulated saliva specimens each morning for two consecutive menstrual cycles. On the basis of presence/timing of hormone peaks, two investigators classified 24 cycles as normal, 10 as likely normal, and 10 as clearly not normal with respect to expected profiles. Our results show that whole saliva samples collected at home on a daily basis provide a noninvasive, feasible method of determining menstrual cycle profiles.
本研究的目的是根据自行采集的唾液样本中的孕酮和雌二醇水平来描述月经周期的正常情况。22名年龄在19至40岁之间的女性，在连续两个月经周期的每天早晨自行采集未受刺激的全唾液样本。根据激素峰值的出现情况/时间，两名研究人员将24个周期分类为正常，10个可能正常，10个明显不符合预期特征，即不正常。我们的结果表明，每天在家中采集的全唾液样本提供了一种非侵入性的、可行的确定月经周期特征的方法。
