Freire Rafael C, Lopes Fabiana L, Veras André B, Valença Alexandre M, Mezzasalma Marco A, Nascimento Isabella, Nardi Antonio E
Laboratory of Panic and Respiration,, Institute of Psychiatry, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
Braz J Psychiatry. 2007 Mar;29(1):31-4. doi: 10.1590/s1516-44462007000100010.
Our aim was to identify the personality traits in patients with panics disorder, major depression and with both disorders (comorbidity).
Diagnoses were made with the Structured Clinical Interview for DSM-IV before the treatment, and the personality evaluation with the Maudsley Personality Inventory was made during the follow-up. Four groups were analyzed: a control group (n = 30), a major depression without panic disorder group (n = 45); a panic disorder without major depression group (n = 56) and a comorbidity group (n = 21), with major depression and panic disorder, simultaneously.
All disorder groups had significantly higher neuroticism means when compared to the control group. The highest mean was in the comorbidity group, followed by the major depression group and the panic disorder group. The difference of neuroticism means between the comorbidity group and the panic disorder group also reached statistical significance. The lowest extraversion mean was in the comorbidity group, followed by the major depression group, the panic disorder group, and the control group. Compared to normal controls, extraversion was significantly low in the comorbidity and major depression groups.
In our sample, there was a continuum of personality traits between panic disorder and major depression and, the co-occurrence of these disorders was associated with accentuated personality traits.
我们的目的是确定恐慌症患者、重度抑郁症患者以及同时患有这两种疾病（共病）的患者的人格特质。
在治疗前使用《精神疾病诊断与统计手册》第四版（DSM-IV）的结构化临床访谈进行诊断，并在随访期间使用莫兹利人格量表进行人格评估。分析了四组：对照组（n = 30）、无恐慌症的重度抑郁症组（n = 45）、无重度抑郁症的恐慌症组（n = 56）以及同时患有重度抑郁症和恐慌症的共病组（n = 21）。
与对照组相比，所有疾病组的神经质均值均显著更高。均值最高的是共病组，其次是重度抑郁症组和恐慌症组。共病组与恐慌症组之间的神经质均值差异也具有统计学意义。外向性均值最低的是共病组，其次是重度抑郁症组、恐慌症组和对照组。与正常对照组相比，共病组和重度抑郁症组的外向性显著较低。
在我们的样本中，恐慌症和重度抑郁症之间存在人格特质的连续性，并且这些疾病的共现与人格特质的加剧有关。
