Verjans H L, Eik-Nes K B
Acta Endocrinol (Copenh). 1976 Jan;81(1):198-207. doi: 10.1530/acta.0.0810198.
Effect of intramuscular administration of ACTH or dexamethasone on blood serum levels of testosterone, LH and FSH was examined in intact and castrated, adult, male rats. Six IU ACTH or 1 mg dexamethasone were given daily for 7 days. Corticotrophin treatment had no influence on circulating testosterone, LH and FSH in intact or castrated male rats. Dexamethasone administration resulted in a slight elevation of serum FSH in intact animals but not in castrates. LH and testosterone remained normal in both intact and castrated animals injected with dexamethasone. Under our conditions of study the secretions from the adrenal gland appear to be insignificant for the regulation of pituitary secretion of gonadotrophins in the male rat.
在成年雄性大鼠中，研究了肌内注射促肾上腺皮质激素（ACTH）或地塞米松对完整和去势大鼠血清睾酮、促黄体生成素（LH）和促卵泡生成素（FSH）水平的影响。每天给予6 IU ACTH或1 mg地塞米松，持续7天。促肾上腺皮质激素治疗对完整或去势雄性大鼠的循环睾酮、LH和FSH没有影响。给予地塞米松导致完整动物血清FSH略有升高，但去势动物没有。注射地塞米松的完整和去势动物的LH和睾酮均保持正常。在我们的研究条件下，肾上腺分泌对于雄性大鼠垂体促性腺激素分泌的调节似乎并不重要。
