Stringer Mark D
Department of Anatomy and Structural Biology, Otago School of Medical Sciences, University of Otago, PO Box 913, Dunedin, New Zealand.
Pediatr Surg Int. 2007 Jun;23(6):529-32. doi: 10.1007/s00383-007-1929-3. Epub 2007 Apr 17.
Standard reconstruction after choledochal cyst excision is by Roux-en-Y hepaticojejunostomy to the common hepatic duct. Long-term follow up studies have shown a 10% incidence of late complications, including anastomotic stricture. By extending the bilio-enteric anastomosis along the left hepatic duct, a wide hilar bilio-enteric anastomosis is created which may help to minimize late anastomotic complications. Forty-one consecutive patients (24 girls, 18 infants) with a median age of 2.3 years (range 44 days to 15.6 years) and median weight 11.5 kg (range 2.1-59 kg) underwent radical choledochal cyst excision with a wide hilar hepaticojejunostomy. Thirty-eight were followed-up both clinically and by ultrasound scan and biochemical liver function tests for a median of 2.7 years (range 0.1-12.5 years). The median width of the hilar hepaticojejunostomy was 8 mm (range 6-25 mm) in 18 infants, and 15 mm (range 10-25 mm) in 22 older children. In one patient it was not measured. Only one surgical complication occurred--a self-limiting bile leak which settled spontaneously. Median postoperative stay was 6 days (range 5-21 days). No patient has had an episode of cholangitis or adhesive small bowel obstruction to date. Postoperative biochemical liver function tests have remained normal in all but one child (with pre-existing biliary cirrhosis). After radical resection of a choledochal cyst, a wide hilar hepaticojejunostomy is a, safe, effective and durable reconstructive technique that can be performed at any age and may help to minimize the long-term risk of complications.
胆总管囊肿切除术后的标准重建方法是行 Roux-en-Y 肝管空肠吻合术至肝总管。长期随访研究表明,晚期并发症的发生率为 10%,包括吻合口狭窄。通过沿左肝管延长胆肠吻合口,可形成一个宽大的肝门部胆肠吻合口,这可能有助于将晚期吻合口并发症降至最低。41 例连续患者(24 名女孩,18 名婴儿),中位年龄 2.3 岁(范围 44 天至 15.6 岁),中位体重 11.5 kg(范围 2.1 - 59 kg),接受了根治性胆总管囊肿切除术及宽大的肝门部肝管空肠吻合术。38 例患者接受了临床随访,并通过超声扫描和生化肝功能检查,中位随访时间为 2.7 年(范围 0.1 - 12.5 年)。18 例婴儿肝门部肝管空肠吻合口的中位宽度为 8 mm(范围 6 - 25 mm),22 例大龄儿童为 15 mm(范围 10 - 25 mm)。1 例患者未测量。仅发生 1 例手术并发症——自限性胆漏,自行愈合。术后中位住院时间为 6 天(范围 5 - 21 天)。迄今为止,无患者发生胆管炎或粘连性小肠梗阻。除 1 名儿童(术前存在胆汁性肝硬化)外,所有患者术后生化肝功能检查均保持正常。根治性切除胆总管囊肿后,宽大的肝门部肝管空肠吻合术是一种安全、有效且持久的重建技术,可在任何年龄实施,且可能有助于将长期并发症风险降至最低。