Santucci Richard A, Joyce Geoffrey F, Wise Matthew
Department of Urology, Wayne State University School of Medicine, Detroit, Michigan 48201, USA.
J Urol. 2007 May;177(5):1667-74. doi: 10.1016/j.juro.2007.01.041.
The incidence of urethral stricture disease in the United States is unknown. We estimated the impact of urethral stricture disease by determining its prevalence, costs and other measures of burden, including side effects and the need for surgical intervention.
Analyses of services for urethral stricture disease were performed in 10 public and private data sets by epidemiological, biostatistical and clinical experts.
Male urethral stricture disease occurred at a rate as high as 0.6% in some susceptible populations and resulted in more than 5,000 inpatient visits yearly. Yearly office visits for urethral stricture numbered almost 1.5 million between 1992 and 2000. The total cost of urethral stricture diseases in 2000 was almost $200 million, not including medication costs. A diagnosis of urethral stricture increased health care expenditures by more than $6,000 per individual yearly in insured populations after controlling for comorbidities. Urethral stricture disease appeared to be more common in the elderly population and in black patients, as measured by health care use. In most data sets services provided for urethral stricture disease decreased with time. Patients with urethral stricture disease appeared to have a high rate of urinary tract infection (41%) and incontinence (11%).
Despite decreasing rates of urethral strictures with time the burden of urethral stricture disease is still significant, resulting in hundreds of millions of dollars spent and hundreds of thousands of caregiver visits yearly.
美国尿道狭窄疾病的发病率尚不清楚。我们通过确定其患病率、成本及其他负担指标(包括副作用和手术干预需求)来评估尿道狭窄疾病的影响。
流行病学、生物统计学和临床专家对10个公共和私人数据集进行了尿道狭窄疾病服务分析。
在一些易感人群中,男性尿道狭窄疾病的发生率高达0.6%,每年导致超过5000人次住院。1992年至2000年间,每年因尿道狭窄进行的门诊就诊次数近150万次。2000年尿道狭窄疾病的总成本近2亿美元,不包括药物成本。在控制合并症后,尿道狭窄诊断使参保人群中每人每年的医疗保健支出增加超过6000美元。从医疗保健使用情况来看,尿道狭窄疾病在老年人群和黑人患者中似乎更为常见。在大多数数据集中,为尿道狭窄疾病提供的服务随时间减少。尿道狭窄疾病患者似乎有较高的尿路感染率(41%)和尿失禁率(11%)。
尽管尿道狭窄发生率随时间下降,但尿道狭窄疾病的负担仍然很大,每年导致数亿美元的支出和数十万次的护理就诊。