French C E, Antoine D, Gelb D, Jones J A, Gilbert R L, Watson J M
Tuberculosis Section, Respiratory Diseases Department, Health Protection Agency Centre for Infections, London, United Kingdom.
Int J Tuberc Lung Dis. 2007 May;11(5):577-84.
England and Wales, 2001-2003.
To describe demographic and clinical characteristics of tuberculosis (TB) in non-UK-born persons and compare with UK-born cases to inform public health action and health service provision.
Analysis of surveillance data.
Among the 67% of cases who were non-UK-born, TB incidence was 88/100000 compared to 4/100000 among the UK-born. UK-born minority ethnic groups were also at increased risk of TB. Although the highest TB incidence occurred in recent entrants to the UK, nearly half the cases had been resident for >or=5 years. The majority of non-UK-born cases originated from South Asia (48%) and sub-Saharan Africa (35%). The demographic characteristics of non-UK-born and UK-born cases differed. In addition, non-UK-born cases were less likely to have pulmonary TB than the UK-born (52% vs. 73%, chi(2) P<0.001), but were more likely to have isoniazid-resistant disease (8% vs. 6%, chi(2) P=0.002), depending on region of birth.
During 2001-2003, most TB cases were non-UK-born. TB services need to take the characteristics of TB in this group into account. Furthermore, awareness of the risk of disease is required among the non-UK-born for many years after arrival into the UK, and among UK-born minority ethnic groups.
2001 - 2003年，英格兰和威尔士。
描述非英国出生人群中结核病（TB）的人口统计学和临床特征，并与英国出生的病例进行比较，以为公共卫生行动和医疗服务提供提供信息。
监测数据分析。
在67%非英国出生的病例中，结核病发病率为88/10万，而英国出生的病例中发病率为4/10万。英国出生的少数族裔患结核病的风险也有所增加。虽然结核病发病率最高的是刚进入英国的人，但近一半的病例已在英国居住≥5年。大多数非英国出生的病例来自南亚（48%）和撒哈拉以南非洲（35%）。非英国出生和英国出生病例的人口统计学特征不同。此外，非英国出生的病例患肺结核的可能性低于英国出生的病例（52%对73%，卡方检验P<0.001），但根据出生地区不同，患耐异烟肼疾病的可能性更高（8%对6%，卡方检验P = 0.002）。
在2001 - 2003年期间，大多数结核病病例是非英国出生的。结核病服务需要考虑到这一群体中结核病的特征。此外，非英国出生的人在抵达英国多年后以及英国出生的少数族裔群体都需要了解疾病风险。
