Park Jong-Seon, Shin Dong-Gu, Kim Young-Jo, Hong Gu-Ru, Kim Woong, Lee Sang-Hee, Shim Bong-Sup
Int J Cardiol. 2007 Jul 10;119(2):e35-7. doi: 10.1016/j.ijcard.2007.01.092. Epub 2007 Apr 17.
Noncompaction of ventricular myocardium (NVM) is a morphogenetic anomaly of ventricular myocardium that leads to the development of cardiomyopathy. It is frequently associated with other congenital cardiac malformations. A 75-year-old woman was admitted with resting dyspnea lasting for several days. Two-dimensional echocardiography demonstrated an enlarged left ventricle with global impairment of systolic function. The myocardial trabeculations, with multiple recesses, were observed at the apex and mid-ventricular segment of the left ventricle. Contrast echocardiography showed filling of the recesses with the contrast agent. Dynamic contrast magnetic resonance imaging also showed distinctive features of NVM corresponding to the echocardiographic findings. In addition, a coronary artery originating from the proximal ascending aorta was observed. Aortogram and coronary angiography confirmed that the coronary artery had an aberrant origin from the ascending aorta and right coronary artery was an anomalous origin from left anterior descending coronary artery. This case suggests that NVM can present with other life threatening cardiovascular anomalies and different imaging studies are helpful for a comprehensive diagnosis.
心室心肌致密化不全（NVM）是一种心室心肌的形态发生异常，可导致心肌病的发生。它常与其他先天性心脏畸形相关。一名75岁女性因持续数天的静息性呼吸困难入院。二维超声心动图显示左心室扩大，收缩功能整体受损。在左心室心尖和心室中段观察到有多个隐窝的心肌小梁。对比增强超声心动图显示造影剂充盈隐窝。动态对比增强磁共振成像也显示出与超声心动图结果相符的NVM特征。此外，还观察到一条冠状动脉起源于升主动脉近端。主动脉造影和冠状动脉造影证实该冠状动脉起源于升主动脉异常，右冠状动脉起源于左前降支冠状动脉异常。该病例表明，NVM可伴有其他危及生命的心血管异常，不同的影像学检查有助于综合诊断。
