Testa A C, Ferrandina G, Timmerman D, Savelli L, Ludovisi M, Van Holsbeke C, Malaggese M, Scambia G, Valentin L
Gynecologic Oncology Unit, Catholic University of Sacred Heart, Rome, Italy, and Department of Obstetrics and Gynecology, University Hospitals KU Leuven, Belgium.
Ultrasound Obstet Gynecol. 2007 May;29(5):505-11. doi: 10.1002/uog.4020.
To describe the gray-scale and color Doppler ultrasound findings of metastatic tumors in the ovary according to the origin of the primary tumor.
Information was retrieved retrospectively from 67 patients who had undergone preoperative transvaginal gray-scale and color Doppler ultrasound examination and who were found subsequently to have metastatic tumors in their ovaries. In all women the ultrasound information had been collected prospectively using a standardized examination technique and predefined definitions of ultrasound characteristics. Stored ultrasound images were used only to describe retrospectively the external surface of the metastatic tumors. Information on presenting symptoms and on whether the patient had been treated for a malignancy in the past was retrieved retrospectively from patient records.
Most (95%) ovarian metastases were solid, multilocular-solid or multilocular. Almost all (38/41, 93%) metastases that derived from the stomach, breast, lymphoma or uterus were solid, while most (16/22, 73%) metastases deriving from the colon, rectum, appendix or biliary tract were multilocular or multilocular-solid (P<0.0001). Metastases that derived from the colon, rectum, appendix or biliary tract were larger compared with those from the stomach, breast, lymphoma or uterus (median maximum diameter, 122 (range, 16-200) mm vs. 71 (range, 27-170) mm, P=0.02). In addition, irregular external borders were more common (19/22 (86%) vs. 19/41 (46%), P=0.002), as were papillary projections (6/22 (27%) vs. 2/41 (5%), P=0.011). They also appeared to be less vascularized, with 64% (14/22) manifesting moderate-to-abundant vascularization at color Doppler examination in comparison to 88% (36/41) of the ovarian metastases from stomach, breast, lymphoma or uterus (P=0.024).
Ovarian metastases derived from lymphoma or from tumors in the stomach, breast and uterus are solid in almost all cases, whereas those derived from the colon, rectum or biliary tract manifest more heterogeneous morphological patterns, most being multicystic with irregular borders.
根据原发性肿瘤的起源描述卵巢转移性肿瘤的灰阶及彩色多普勒超声表现。
回顾性检索67例术前行经阴道灰阶及彩色多普勒超声检查且随后被发现卵巢有转移性肿瘤患者的资料。所有女性患者的超声信息均采用标准化检查技术和超声特征的预定义进行前瞻性收集。存储的超声图像仅用于回顾性描述转移性肿瘤的外表面。回顾性从患者记录中获取有关症状表现以及患者既往是否接受过恶性肿瘤治疗的信息。
大多数（95%）卵巢转移瘤为实性、多房实性或多房性。几乎所有源自胃、乳腺、淋巴瘤或子宫的转移瘤（38/41，93%）为实性，而大多数源自结肠、直肠、阑尾或胆道的转移瘤（16/22，73%）为多房性或多房实性（P<0.0001）。源自结肠、直肠、阑尾或胆道的转移瘤比源自胃、乳腺、淋巴瘤或子宫的转移瘤更大（最大直径中位数，122（范围16 - 200）mm对71（范围27 - 170）mm，P = 0.02）。此外，不规则的外部边界更常见（19/22（86%）对19/41（46%），P = 0.002），乳头状突起也是如此（6/22（27%）对2/41（5%），P = 0.011）。它们的血管化程度似乎也较低，彩色多普勒检查显示64%（14/22）表现为中度至丰富的血管化，相比之下，源自胃、乳腺、淋巴瘤或子宫的卵巢转移瘤为88%（36/41）（P = 0.024）。
几乎所有源自淋巴瘤或胃、乳腺及子宫肿瘤的卵巢转移瘤为实性，而源自结肠、直肠或胆道的转移瘤表现出更多样化的形态学模式，大多数为边界不规则的多囊性。
