Koupil I
Centre for Health Equity Studies (CHESS), Stockholm University/Karolinska Institute, Stockholm, Sweden.
J Intern Med. 2007 May;261(5):426-36. doi: 10.1111/j.1365-2796.2007.01799.x.
Large-scale epidemiological studies on developmental origins of health running in Uppsala benefit from the accessibility of well-archived and high quality Swedish records, high participation rates in the surveys, and a long tradition of interdisciplinary research and international collaboration. The UBCoS Multigen study is unique in being able to study intergenerational determinants of health and health inequalities as 'forward in time' processes, starting at the beginning of the last century, whilst the Uppsala Family and ULSAM studies contribute evidence on gene-environment interactions and specific mechanisms of developmental origins of circulatory diseases.
在乌普萨拉开展的关于健康发育起源的大规模流行病学研究受益于瑞典保存完好且高质量的记录的可获取性、调查中的高参与率以及跨学科研究和国际合作的悠久传统。英属哥伦比亚大学多基因研究（UBCoS Multigen study）的独特之处在于能够将健康和健康不平等的代际决定因素作为“时间向前”的过程进行研究，该研究始于上世纪初，而乌普萨拉家庭研究和乌普萨拉老年男性前瞻性研究（ULSAM）则为基因与环境的相互作用以及循环系统疾病发育起源的具体机制提供了证据。
