Holsti Liisa, Grunau Ruth E, Shany Eilon
Developmental Neurosciences & Child Health, Child & Family Research Institute, Vancouver, Canada.
Pain Manag. 2011 Mar 1;1(2):171-179. doi: 10.2217/pmt.10.19.
Preterm infants in the neonatal intensive care unit undergo repeated exposure to procedural and ongoing pain. Early and long-term changes in pain processing, stress-response systems and development may result from cumulative early pain exposure. So that appropriate treatment can be given, accurate assessment of pain is vital, but is also complex because these infants' responses may differ from those of full-term infants. A variety of uni- and multidimensional assessment tools are available; however, many have incomplete psychometric testing and may not incorporate developmentally important cues. Near-infrared spectroscopy and/or EEG techniques that measure neonatal pain responses at a cortical level offer new opportunities to validate neonatal pain assessment tools.
新生儿重症监护病房中的早产儿会反复经历程序性疼痛和持续性疼痛。早期累积的疼痛暴露可能导致疼痛处理、应激反应系统和发育方面的早期及长期变化。为了能够给予适当的治疗，准确评估疼痛至关重要，但也很复杂，因为这些婴儿的反应可能与足月儿不同。有多种单维和多维评估工具可供使用；然而，许多工具的心理测量测试并不完整，可能没有纳入对发育重要的线索。在皮层水平测量新生儿疼痛反应的近红外光谱和/或脑电图技术为验证新生儿疼痛评估工具提供了新的机会。
