Pusztaszeri Marc, Hauser Johannes, Iselin Christophe, Egger Jean-François, Pelte Marie-Françoise
Department of Clinical Pathology, University Hospital Geneva, Geneva, Switzerland.
Urology. 2007 Apr;69(4):778.e15-7. doi: 10.1016/j.urology.2007.02.017.
The nested variant of urothelial carcinoma is a rare type of urothelial invasive carcinoma. It is characterized by islands of discrete to moderate atypical urothelial cells that strongly simulate von Brunn nests and invade to the lamina propria or deeper. Almost all described cases have been located in the bladder. We report a case of nested variant of urothelial carcinoma of the renal pelvis and ureter, synchronous with high-grade urothelial papillary carcinoma.
尿路上皮癌的巢状变异型是一种罕见的尿路上皮浸润性癌。其特征是由离散至中等程度的非典型尿路上皮细胞组成的巢团,这些巢团强烈模拟冯布伦巢,并浸润至固有层或更深层。几乎所有已报道的病例都位于膀胱。我们报告一例肾盂和输尿管尿路上皮癌巢状变异型病例,与高级别尿路上皮乳头状癌同时存在。