Akhavan Ardavan, Yin Ming, Benoit Ronald
Department of Urology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15232, USA.
Urology. 2007 Apr;69(4):778.e9-10. doi: 10.1016/j.urology.2007.02.010.
Tumor cytoreduction combined with intraperitoneal hyperthermic chemotherapy has been shown to be an effective method to delay the progression of peritoneal carcinomatosis. We describe 2 cases of painful scrotal ulcer after tumor debulking and intraperitoneal infusion of mitomycin-C for treatment of metastatic abdominal malignancies. Although the pathogenesis is unknown, the awareness of its presence and early signs of clinical presentations by clinicians is very important.
肿瘤细胞减灭术联合腹腔热灌注化疗已被证明是延缓腹膜癌转移进展的有效方法。我们描述了2例在肿瘤减瘤术及腹腔内注入丝裂霉素-C治疗转移性腹部恶性肿瘤后出现疼痛性阴囊溃疡的病例。尽管其发病机制尚不清楚,但临床医生了解其存在及临床表现的早期体征非常重要。