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6例成釉细胞瘤的超微结构研究

[Ultrastructural study of 6 cases of ameloblastoma].

作者信息

Brocheriou C, Hauw J J, Auriol M, Guilbert F, Cernea P, Chomette G

出版信息

Ann Anat Pathol (Paris). 1975 May-Jul;20(3):231-44.

PMID:174462
Abstract

Three cases of simple ameloblastoma were studied by electron microscopy. The classical ultrastructural features of these tumors are analysed and compared with reports in the literature and the development of the enamel organ. The authors stress the presence of two cell types (light and dark) probably corresponding to different degrees of maturity. One case of cystic ameloblastoma and one of granular cell ameloblastoma are then reported. The nature of the inclusions in this latter tumour is probably mixed: lysomal and secretory, perhaps ameloblastic. Finally, a malignant ameloblastoma is described under electron microscopy, for the first time. Closely related to simple ameloblastomas, it may be distinguished only by the presence of signs of cellular degeneration and numerous mitoses, sometimes abnormal.

摘要

对三例单纯性成釉细胞瘤进行了电子显微镜研究。分析了这些肿瘤的经典超微结构特征,并与文献报道以及釉质器的发育情况进行了比较。作者强调存在两种细胞类型(亮细胞和暗细胞),可能对应不同程度的成熟度。随后报告了一例囊性成釉细胞瘤和一例颗粒细胞成釉细胞瘤。后一种肿瘤中包涵体的性质可能是混合性的:溶酶体性和分泌性的,或许还有成釉细胞性的。最后,首次在电子显微镜下描述了一例恶性成釉细胞瘤。它与单纯性成釉细胞瘤密切相关,可能仅通过细胞变性迹象和大量有丝分裂(有时异常)来区分。

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