Koconis Kristen Gledhill, Singh Harjit, Soares Gregory
Department of Radiology, Penn State Heart and Vascular Institute, Pennsylvania State Milton S. Hershey Medical Center, 500 University Drive, Hershey, PA 17033, USA.
J Vasc Interv Radiol. 2007 Apr;18(4):463-81. doi: 10.1016/j.jvir.2006.12.734.
This article reviews the existing literature on the use of partial splenic embolization in patients with portal hypertension. All articles published in the English language on splenic embolization or partial splenic embolization as a treatment for portal hypertension were identified with a PubMed search from 1973 through 2005. Partial splenic embolization appears to be efficacious in reducing episodes of variceal bleeding, improving hematologic parameters, enhancing hepatic protein synthesis, and reducing the severity of hepatic encephalopathy. Associated morbidity and mortality appear to be acceptable. The literature, however, is limited in quality. Given the potential benefits of partial splenic embolization, further investigation is warranted to allow evidence-based evaluation of its use.
本文综述了关于门静脉高压患者使用部分脾栓塞术的现有文献。通过对1973年至2005年PubMed数据库的检索,确定了所有以英文发表的关于脾栓塞术或部分脾栓塞术治疗门静脉高压的文章。部分脾栓塞术在减少静脉曲张出血发作、改善血液学参数、增强肝脏蛋白质合成以及降低肝性脑病严重程度方面似乎是有效的。相关的发病率和死亡率似乎是可以接受的。然而,文献质量有限。鉴于部分脾栓塞术的潜在益处,有必要进行进一步研究,以便对其使用进行循证评估。