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病例报告：部分脾动脉栓塞术治疗非肝硬化门静脉高压继发的疼痛性脾肿大

Case Report: Partial Splenic Artery Embolization for the Treatment of Painful Splenomegaly Secondary to Noncirrhotic Portal Hypertension.

作者信息

Kratzer Logan, Waters Maddison, Parkes Simon, Cheung Nicholas, Shackel Nicholas

机构信息

Department of Gastroenterology, Launceston General Hospital, Launceston, Tasmania, Australia.

Tasmanian School of Medicine, University of Tasmania, Launceston, Tasmania, Australia.

出版信息

Case Reports Hepatol. 2025 Jun 6;2025:9303407. doi: 10.1155/crhe/9303407. eCollection 2025.

DOI:10.1155/crhe/9303407
PMID:40519795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12165750/
Abstract

Noncirrhotic portal hypertension (NCPH) is a rare cause of portal hypertension with varied etiologies. We present two cases of painful splenomegaly secondary to NCPH successfully treated with partial splenic artery embolization (PSE). Despite limited literature on PSE's efficacy for NCPH-related painful splenomegaly, our cases demonstrate significant pain relief and reduction in opiate dependence postprocedure. Imaging revealed substantial decreases in spleen size without major complications. PSE emerges as a promising therapeutic option for NCPH-related painful splenomegaly, offering improved quality of life and reduced reliance on analgesics.

摘要

非肝硬化性门静脉高压（NCPH）是门静脉高压的一种罕见病因，病因多样。我们报告了两例继发于NCPH的疼痛性脾肿大病例，通过部分脾动脉栓塞术（PSE）成功治疗。尽管关于PSE治疗NCPH相关疼痛性脾肿大疗效的文献有限，但我们的病例显示术后疼痛显著缓解，阿片类药物依赖减少。影像学检查显示脾脏大小显著减小，无重大并发症。PSE成为治疗NCPH相关疼痛性脾肿大的一种有前景的治疗选择，可提高生活质量并减少对镇痛药的依赖。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/105b/12165750/6e0f3ab42ce7/CRIHEP2025-9303407.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/105b/12165750/42997c8f5ddb/CRIHEP2025-9303407.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/105b/12165750/6e0f3ab42ce7/CRIHEP2025-9303407.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/105b/12165750/42997c8f5ddb/CRIHEP2025-9303407.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/105b/12165750/6e0f3ab42ce7/CRIHEP2025-9303407.002.jpg

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本文引用的文献

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Outcomes of partial splenic embolization in patients with massive splenomegaly due to idiopathic portal hypertension.特发性门静脉高压所致巨脾患者行部分脾栓塞术的疗效
World J Gastroenterol. 2016 Nov 21;22(43):9623-9630. doi: 10.3748/wjg.v22.i43.9623.
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