Ray Lara A, Meskew-Stacer Shaneen, Hutchison Kent E
University of Colorado, Department of Psychology, Boulder, CO, USA.
J Stud Alcohol Drugs. 2007 May;68(3):379-84. doi: 10.15288/jsad.2007.68.379.
Determining whether individuals can provide accurate reports of alcohol sensitivity and craving, outside of a laboratory alcohol challenge, has important research and clinical implications. The primary goals of the present study are (1) to test the relationship between prospective self-ratings of the effects of alcohol and alcohol craving, and experimental results from alcohol challenge studies and (2) to examine potential moderators of that relationship.
Participants were heavy drinkers who completed either an intravenous (n = 49) or an oral administration (n = 135) alcohol challenge. Participants were asked to estimate their craving for alcohol in a drinking situation and their subjective intoxication after consuming three drinks. Subjective intoxication and alcohol craving were then assessed during the laboratory alcohol challenge.
Estimated subjective intoxication and alcohol craving were significant predictors of subjective intoxication and craving measured under laboratory conditions and accounted for, at most, 16% and 37%, respectively, of the variance in laboratory measures.
Taken together, these findings suggest that sensitivity to the effects of alcohol and alcohol craving may be measured outside of the laboratory but that scales that are especially designed for nonlaboratory studies may be required.
确定个体在实验室酒精激发试验之外能否准确报告酒精敏感性和渴望程度，具有重要的研究和临床意义。本研究的主要目标是：（1）检验酒精效应的前瞻性自我评分与酒精渴望之间的关系，以及酒精激发试验研究的实验结果；（2）考察该关系的潜在调节因素。
参与者为重度饮酒者，他们完成了静脉注射（n = 49）或口服酒精激发试验（n = 135）。要求参与者估计在饮酒情境下对酒精的渴望程度以及饮用三杯酒后的主观醉酒程度。然后在实验室酒精激发试验期间评估主观醉酒程度和酒精渴望程度。
估计的主观醉酒程度和酒精渴望程度是实验室条件下测量的主观醉酒程度和渴望程度的显著预测指标，分别最多解释了实验室测量结果中16%和37%的方差。
综合来看，这些发现表明酒精效应敏感性和酒精渴望程度可能可以在实验室之外进行测量，但可能需要专门为非实验室研究设计的量表。
