Kato Takema, Yamada Kouji, Inagaki Hidehito, Kogo Hiroshi, Ohye Tamae, Emanuel Beverly S, Kurahashi Hiroki
Division of Molecular Genetics, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Japan.
Fertil Steril. 2007 Nov;88(5):1446-8. doi: 10.1016/j.fertnstert.2007.01.019. Epub 2007 Apr 19.
We analyzed de novo constitutional t(11;22) translocation frequency in sperm derived from normal healthy males as a function of the age of the sperm donors (from 25 to 51). Translocation-specific polymerase chain reaction demonstrated no age-dependent increment in the frequency of the rearrangements.
我们分析了来自正常健康男性的精子中新生性染色体11;22易位频率与精子供体年龄(25至51岁)之间的关系。易位特异性聚合酶链反应表明,重排频率没有随年龄增长而增加。