Blizzard Timothy A, Gude Candido, Chan Wanda, Birzin Elizabeth T, Mojena Marina, Tudela Consuelo, Chen Fang, Knecht Kristin, Su Qin, Kraker Bryan, Holmes Mark A, Rohrer Susan P, Hammond Milton L
Merck Research Laboratories, PO Box 2000, Rahway, NJ 07065, USA.
Bioorg Med Chem Lett. 2007 May 15;17(10):2944-8. doi: 10.1016/j.bmcl.2006.12.053. Epub 2006 Dec 21.
A series of bridged androstenediol derivatives was prepared. The bridged compounds exhibited reduced ER-beta selectivity relative to uncyclized analogs.
