Cellot Sonia, Sauvageau Guy
Laboratory of Molecular Genetics of Stem Cells, Institute for Research in Immunology and Cancer (IRIC), C.P. 6128 succursale Centre-Ville, Montréal, Québec H3C 3J7, Canada.
Cell. 2007 Apr 20;129(2):239-41. doi: 10.1016/j.cell.2007.04.002.
As the molecular mechanisms that govern stem cell fate are beginning to be unraveled, Galan-Caridad et al. (2007) report in this issue of Cell a common role for the transcription factor Zfx in the self-renewal/maintenance of both embryonic stem cells and hematopoietic stem cells. Their work suggests that a regulator of self-renewal can be shared between two different cell types.
随着调控干细胞命运的分子机制开始被揭示，加兰 - 卡里达德等人（2007年）在本期《细胞》杂志上报道，转录因子Zfx在胚胎干细胞和造血干细胞的自我更新/维持中发挥共同作用。他们的研究表明，自我更新的调节因子可以在两种不同的细胞类型之间共享。
