Yoshizumi Terry T, Goodman Philip C, Frush Donald P, Nguyen Giao, Toncheva Greta, Sarder Maksudur, Barnes Lottie
Department of Radiology, Duke University Medical Center, Box 3155, Durham, NC 27710, USA.
AJR Am J Roentgenol. 2007 May;188(5):1332-6. doi: 10.2214/AJR.06.0742.
The purposes of this study were to apply near-real-time dose-measurement technology with metal oxide semiconductor field effect transistors (MOSFETs) to the assessment of organ dose during CT and to validate the method in comparison with the thermoluminescent dosimeter (TLD) method.
Dosimetry measurements were performed in two ways, one with TLDs and the other with MOSFETs. Twenty organ locations were selected in an adult anthropomorphic female phantom. High-sensitivity MOSFET dosimeters were used. For the reference standard, TLDs were placed in the same organ locations as the MOSFETs. Both MOSFET and TLD detectors were calibrated with an X-ray beam equivalent in quality to that of a commercial CT scanner (half-value layer, approximately 7 mm Al at 120 kVp). Organ dose was determined with a scan protocol for pulmonary embolus studies on a 4-MDCT scanner.
Measurements for selected organ doses and the percentage difference for TLDs and MOSFETs, respectively, were as follows: thyroid (0.34 cGy, 0.31 cGy, -8%), middle lobe of lung (2.4 cGy, 3.0 cGy, +26%), bone marrow of thoracic spine (2.2 cGy, 2.5 cGy, +11%), stomach (1.0 cGy, 0.93 cGy, -6%), liver (2.5 cGy, 2.6 cGy, +6%), and left breast (3.0 cGy, 2.9 cGy, -1%). Bland-Altman analysis showed that the MOSFET results agreed with the TLD results (bias, 0.042).
We found good agreement between the results with the MOSFET and TLD methods. Near-real-time CT organ dose assessment not previously feasible with TLDs was achieved with MOSFETs. MOSFET technology can be used for protocol development in the rapidly changing MDCT scanner environment, in which organ dose data are extremely limited.
本研究的目的是将金属氧化物半导体场效应晶体管(MOSFET)近实时剂量测量技术应用于CT检查期间器官剂量的评估,并与热释光剂量计(TLD)方法相比对该方法进行验证。
剂量测定采用两种方式进行,一种使用TLD,另一种使用MOSFET。在成年女性仿真人体模型中选择了20个器官位置。使用了高灵敏度MOSFET剂量计。作为参考标准,TLD放置在与MOSFET相同的器官位置。MOSFET和TLD探测器均用质量与商用CT扫描仪相当的X射线束(在120 kVp时半值层约为7 mm铝)进行校准。使用4层MDCT扫描仪上用于肺栓塞研究的扫描方案确定器官剂量。
所选器官剂量的测量值以及TLD和MOSFET的百分比差异分别如下:甲状腺(0.34 cGy,0.31 cGy,-8%)、肺中叶(2.4 cGy,3.0 cGy,+26%)、胸椎骨髓(2.2 cGy,2.5 cGy,+11%)、胃(1.0 cGy,0.93 cGy,-6%)、肝脏(2.5 cGy,2.6 cGy,+6%)和左乳房(3.0 cGy,2.9 cGy,-1%)。Bland-Altman分析表明MOSFET结果与TLD结果一致(偏差为0.042)。
我们发现MOSFET方法和TLD方法的结果之间具有良好的一致性。MOSFET实现了以前TLD无法实现的近实时CT器官剂量评估。MOSFET技术可用于快速变化的MDCT扫描仪环境中的方案制定,在该环境中器官剂量数据极其有限。