Simonoff Emily, Pickles Andrew, Wood Nicky, Gringras Paul, Chadwick Oliver
Dr. Simonoff and Ms. Wood are with the Department of Child and Adolescent Psychiatry, King's College London, Institute of Psychiatry, London; Dr. Pickles is with the Biostatistics Group, Division of Epidemiology and Health Science, University of Manchester, Manchester, UK; Dr. Gringras is with Guy's and St. Thomas' Hospitals NHS Trust, London; and Dr. Chadwick is with the Department of Psychology, King's College London, Institute of Psychiatry, London.
Dr. Simonoff and Ms. Wood are with the Department of Child and Adolescent Psychiatry, King's College London, Institute of Psychiatry, London; Dr. Pickles is with the Biostatistics Group, Division of Epidemiology and Health Science, University of Manchester, Manchester, UK; Dr. Gringras is with Guy's and St. Thomas' Hospitals NHS Trust, London; and Dr. Chadwick is with the Department of Psychology, King's College London, Institute of Psychiatry, London.
J Am Acad Child Adolesc Psychiatry. 2007 May;46(5):591-600. doi: 10.1097/chi.0b013e3180323330.
To determine whether the nature and correlates of attention-deficit/hyperactivity disorder (ADHD) symptoms are different in subjects with mild intellectual disability (ID) compared to subjects with average ability.
From a general population sample of 2,726 12- to 15-year-olds, a stratified subsample was selected to enrich for mild ID. A total of 192 subjects were included in the analyses. ADHD symptoms and other emotional/behavioral problems were measured with the parent and teacher Strengths and Difficulties Questionnaire and IQ with the WISC-III-UK), and social communication difficulties were assessed by a short version of the Social Communication Questionnaire and academic attainments by the Wechsler Quicktest.
There was a negative linear relationship between ADHD symptoms and IQ (beta = -.087, p <.001). The relationship could not be explained by inappropriate rater expectations. Neither the profiles of ADHD symptoms nor the comorbidity with emotional/behavioral problems differed according to the presence of ID. When IQ was accounted for, the group difference in attainments was nonsignificant.
ADHD symptoms are increased in people with ID. We found no evidence that this increase can by explained by inappropriate expectations or by confounding associations with other emotional/behavioral or cognitive problems.
确定与平均能力的受试者相比,轻度智力障碍(ID)受试者的注意力缺陷/多动障碍(ADHD)症状的性质及相关因素是否存在差异。
从2726名12至15岁的普通人群样本中,选取一个分层子样本以富集轻度ID患者。共有192名受试者纳入分析。使用家长和教师版的长处与困难问卷测量ADHD症状及其他情绪/行为问题,使用韦氏儿童智力量表第三版(英国版)测量智商,使用社会沟通问卷简版评估社会沟通困难,并使用韦氏快速测验评估学业成绩。
ADHD症状与智商之间存在负线性关系(β = -0.087,p <.001)。该关系无法用评估者的不恰当期望来解释。无论是否存在ID,ADHD症状的特征及与情绪/行为问题的共病情况均无差异。在考虑智商因素后,两组在学业成绩上的差异无统计学意义。
ID患者的ADHD症状有所增加。我们没有发现证据表明这种增加可以用不恰当期望或与其他情绪/行为或认知问题的混杂关联来解释。