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核糖体蛋白S14与果蝇中与M(1)7C位点相关的分钟表型无关。

Ribosomal protein S14 is not responsible for the Minute phenotype associated with the M(1)7C locus in Drosophila melanogaster.

作者信息

Dorer D R, Anane-Firempong A, Christensen A C

机构信息

Department of Biochemistry and Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107.

出版信息

Mol Gen Genet. 1991 Nov;230(1-2):8-11. doi: 10.1007/BF00290642.

Abstract

A locus associated with a severe Minute effect has been mapped at 7C on the X chromosome of Drosophila melanogaster. Previous work has suggested that this Minute encodes ribosomal proteins S14A and S14B. We have made a chromosomal deficiency that removes the S14 ribosomal protein genes, yet does not display the Minute phenotype. These data suggest that the S14 genes do not actually correspond to the Minute locus.

摘要

一个与严重的“分钟”效应相关的基因座已被定位在黑腹果蝇X染色体的7C位置。先前的研究表明,这个“分钟”基因编码核糖体蛋白S14A和S14B。我们制造了一个染色体缺失,它去除了S14核糖体蛋白基因,但并未表现出“分钟”表型。这些数据表明,S14基因实际上并不对应于“分钟”基因座。

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