芽生裂殖菌病小鼠模型中的联合疗法
Combined therapies in a murine model of blastoschizomycosis.
作者信息
Serena Carolina, Rodríguez M Mar, Mariné Marçal, Pastor F Javier, Guarro Josep
机构信息
Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Reus, Spain.
出版信息
Antimicrob Agents Chemother. 2007 Jul;51(7):2608-10. doi: 10.1128/AAC.00173-07. Epub 2007 Apr 23.
Abstract
In a murine model of blastoschizomycosis, amphotericin B combined with micafungin, flucytosine or voriconazole did not improve the efficacy of fluconazole. However, such combinations can constitute therapeutic options for those cases where fluconazole fails.
摘要
在芽生裂殖菌病的小鼠模型中，两性霉素B联合米卡芬净、氟胞嘧啶或伏立康唑并不能提高氟康唑的疗效。然而，对于氟康唑治疗失败的病例，这些联合用药可作为治疗选择。
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