Mariné Marçal, Serena Carolina, Fernández-Torres Belkys, Pastor F Javier, Guarro Josep
Unitat de Microbiologia, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Carrer Sant Llorenç 21, 43201, Reus, Spain.
Antimicrob Agents Chemother. 2005 Nov;49(11):4757-9. doi: 10.1128/AAC.49.11.4757-4759.2005.
We compared the efficacies of amphotericin B, fluconazole, flucytosine, and micafungin in a systemic murine infection by three isolates of Candida glabrata. Amphotericin B showed the best results, although none of the drugs dramatically reduced mortality or tissue burden in liver or spleen.
我们比较了两性霉素B、氟康唑、氟胞嘧啶和米卡芬净对光滑念珠菌三个分离株引起的小鼠全身感染的疗效。两性霉素B显示出最佳效果,尽管这些药物均未显著降低死亡率或肝脏或脾脏中的组织负荷。