Koelfen W, Maser P, Korinthenberg R
Universitäts-Kinderklinik Mannheim.
Monatsschr Kinderheilkd. 1991 Sep;139(9):639-42.
A cohort of 74 children three months to 16 years-old who presented with a first unprovoked seizure were followed for five years to assess the risk of recurrence. Children with febrile convulsions, immediate posttraumatic seizures, meningitis and encephalitis were not included. The risk of recurrence was 68% for a second seizure. 47% of the patients developed an epilepsy. 85% of recurrences occurred within the first 6 months and 100% within 2 1/2 years. A history of epilepsy in a first degree relative, age at first seizure, duration of seizure, initial EEG or neurologic status were not associated with significantly higher risk of recurrence.
对74名3个月至16岁首次出现无诱因癫痫发作的儿童进行了为期五年的随访，以评估复发风险。热性惊厥、创伤后即刻发作、脑膜炎和脑炎患儿不包括在内。第二次癫痫发作的复发风险为68%。47%的患者发展为癫痫。85%的复发发生在头6个月内，100%发生在2年半内。一级亲属的癫痫病史、首次癫痫发作时的年龄、发作持续时间、初始脑电图或神经学状态与显著更高的复发风险无关。
