Tsuboi T, Endo S
Neuropadiatrie. 1977 Aug;8(3):209-23. doi: 10.1055/s-0028-1091518.
103 patients with febrile convulsions followed by nonfebrile convulsions and 512 patients with febrile convulsions only (FC group) under 5 years of age at the first examination were analyzed from many aspects. A trimodal curve in distribution by age at onset of nonfebrile convulsions was seen: 2--3 years of age with occasional grand mal, 5--6 years of age with absence, and 12 years of age with awakening grand mal. Specific EEG abnormality was observed in 40% at the first examination (29% in FC group). Typical or atypical spike-and-wave complex, polyspikes, or continuous EEG abnormality were characteristic (slow wave burst with spike for FC group). Development from febrile convulsions into nonfebrile convulsions was detected in 17% among male and female patients. To identify an effective sign for the prediction of this development, the ratio between correct and incorrect prediction rates was analyzed. Specific paroxysmal EEG abnormality was increased over 3 years of age. EEG change due to aging and the significance of EEG reexamination were indicated.
对首次检查时年龄在5岁以下的103例热性惊厥后出现无热惊厥的患儿以及512例仅患有热性惊厥的患儿（热性惊厥组）进行了多方面分析。无热惊厥发病年龄的分布呈三峰曲线：2 - 3岁时有偶尔的全身性强直阵挛发作，5 - 6岁时有失神发作，12岁时有觉醒时全身性强直阵挛发作。首次检查时40%的患儿观察到特异性脑电图异常（热性惊厥组为29%）。典型或非典型的棘慢复合波、多棘波或持续性脑电图异常为其特征（热性惊厥组为伴有棘波的慢波暴发）。在男性和女性患者中，17%的患儿出现了从热性惊厥发展为无热惊厥的情况。为确定预测这种发展的有效指标，分析了正确预测率与错误预测率之间的比例。3岁以上患儿特异性阵发性脑电图异常增多。指出了脑电图随年龄增长的变化以及脑电图复查的意义。
