Cristiano E, Arcega R, Correale J, Gabbay A A, Lander-Delgado R, Macias-Islas M A, Palacios E, Patrucco L, Rivera-Olmos V, Soto A
Hospital Italiano, Buenos Aires, Argentina.
Rev Neurol. 2007;44(8):494-8.
Multiple sclerosis (MS) is the most common primary demyelinating disease affecting the central nervous system. In recent years the development of new drugs that have been shown to modify the natural history of MS have had a substantial impact on the treatment of the disease.
To harmonise and integrate the evidence available on optimising the treatment of patients with MS.
In order to fulfil our main aim, a group of experts from different Latin American countries drew up a list of statements related to the use of immunomodulatory agents in the different clinical forms of the disease and the strategies that should be considered in cases in which the therapeutic response was suboptimal. Each of the participants used a structured scale to express the extent to which he or she agreed or disagreed, and a consensus was considered to have been reached when acceptance of each of the statements was equal to or higher than 80%.
These recommendations will provide neurologists with the tools needed to make decisions that optimise the treatment of MS patients.
多发性硬化症(MS)是影响中枢神经系统最常见的原发性脱髓鞘疾病。近年来,已证实可改变MS自然病程的新药研发对该疾病的治疗产生了重大影响。
协调和整合有关优化MS患者治疗的现有证据。
为实现我们的主要目标,来自不同拉丁美洲国家的一组专家列出了一系列与在该疾病不同临床形式中使用免疫调节药物相关的陈述,以及在治疗反应欠佳情况下应考虑的策略。每位参与者使用结构化量表来表达其同意或不同意的程度,当每条陈述的接受率等于或高于80%时,则认为达成了共识。
这些建议将为神经科医生提供优化MS患者治疗决策所需的工具。