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[切尔诺贝利原子能发电站事故对动物的生物学影响。9. 小鼠免疫活性器官的形态功能指标]

[The biological effects in animals in relation to the accident at the Chernobyl Atomic Electric Power Station. 9. The morphofunctional indices of the immunocompetent organs in mice].

作者信息

Savtsova Z D, Kovbasiuk S A, Iudina O Iu, Zaritskaia M Iu, Voeĭkova I M, Indyk V M, Serkiz Ia I

出版信息

Radiobiologiia. 1991 Sep-Oct;31(5):679-86.

PMID:1745756
Abstract

The permanent action of small doses of low-intensity radiation on the immune status of 2.5-3.5 month CC57W mice has been investigated. Total doses of internal and external irradiation were about few cGy. The permanent action of low-level radiation on the experimental animals of the first and fourth generations was shown to change spleen and lymph nodes weights and the count of lymphocytes isolated from these organs. Cellularity and DNA synthesis in the lymph-node lymphocytes and their proliferative response to polyclonal mitogens also changed. The alterations in the parameters that characterized T-lymphocyte population were statistically significant.

摘要

研究了小剂量低强度辐射对2.5 - 3.5月龄CC57W小鼠免疫状态的长期作用。体内和体外照射的总剂量约为几厘戈瑞。结果表明,低水平辐射对第一代和第四代实验动物的长期作用改变了脾脏和淋巴结的重量以及从这些器官分离出的淋巴细胞数量。淋巴结淋巴细胞的细胞数量、DNA合成及其对多克隆有丝分裂原的增殖反应也发生了变化。表征T淋巴细胞群体的参数变化具有统计学意义。

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