Savtsova Z D, Kovbasiuk S A, Iudina O Iu, Zaritskaia M Iu, Voeĭkova I M, Indyk V M, Serkiz Ia I
Radiobiologiia. 1991 Sep-Oct;31(5):679-86.
The permanent action of small doses of low-intensity radiation on the immune status of 2.5-3.5 month CC57W mice has been investigated. Total doses of internal and external irradiation were about few cGy. The permanent action of low-level radiation on the experimental animals of the first and fourth generations was shown to change spleen and lymph nodes weights and the count of lymphocytes isolated from these organs. Cellularity and DNA synthesis in the lymph-node lymphocytes and their proliferative response to polyclonal mitogens also changed. The alterations in the parameters that characterized T-lymphocyte population were statistically significant.
研究了小剂量低强度辐射对2.5 - 3.5月龄CC57W小鼠免疫状态的长期作用。体内和体外照射的总剂量约为几厘戈瑞。结果表明,低水平辐射对第一代和第四代实验动物的长期作用改变了脾脏和淋巴结的重量以及从这些器官分离出的淋巴细胞数量。淋巴结淋巴细胞的细胞数量、DNA合成及其对多克隆有丝分裂原的增殖反应也发生了变化。表征T淋巴细胞群体的参数变化具有统计学意义。